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Familial Mediterranean fever

Familial Mediterranean fever is an inherited condition characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints

Prevalence

1-5 / 10 000

33,100-165,500

US Estimated

51,350-256,750

Europe Estimated

Age of Onset

ICD-10

E85.0

Inheritance

Autosomal dominant

Autosomal recessive

Mitochondrial/Multigenic

X-linked dominant

X-linked recessive

5 Facts you should know

FACT

An inherited condition characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints

FACT

While all ethnic groups are susceptible to FMF, it usually occurs in people of Mediterranean origin

FACT

Ninety percent of all patients have their first attack before they are 18 years old

FACT

Attacks develop over 2–4 hours and last anywhere from 6 hours to 4 days

FACT

Amyloid A protein is produced in very large quantities during attacks, and at a low rate between attacks, and accumulates mainly in the kidney

Interest over time

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