Rare Immunology News
Advertisement
Disease Profile
Hypertrophic olivary degeneration
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
#N/A
Age of onset
#N/A
ICD-10
#N/A
Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
HOD
Summary
Hypertrophic olivary degeneration (HOD) is a rare neurological condition caused by degeneration in the brain stem, the structure that connects the brain to the spinal cord.[1] Signs and symptoms include palatal tremors, lack of movement coordination (
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
In-Depth Information
- PubMed is a searchable database of medical literature and lists journal articles that discuss Hypertrophic olivary degeneration. Click on the link to view a sample search on this topic.
References
- Sanverdi SE, Oguz KK & Haliloglu G. Hypertrophic olivary degeneration in children: four new cases and a review of the literature with an emphasis on the MRI findings. The British Journal of Radiology. 2012; 85(1013):511-516. https://www.birpublications.org/doi/full/10.1259/bjr/60727602.
- Sabat S, Mannering N & Agarwal A. Hypertrophic olivary degeneration: Case series and review of literature.. J Neurol Sci. November 15, 2016; 370:180-186. https://www.ncbi.nlm.nih.gov/pubmed/27772756.
- Cosentino C & cols.. Bilateral Hypertrophic Olivary Degeneration and Holmes Tremor without Palatal Tremor: An Unusual Association. Louis ED, ed. Tremor and Other Hyperkinetic Movements. 2016; 6:400. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954943/.
- Konno T, Broderick DF, Tacik P, Caviness JN & Wszolek ZK. Hypertrophic olivary degeneration: A clinico-radiologic study. Parkinsonism Relat Disord. July, 2016; 28:36-40. https://www.sciencedirect.com/science/article/pii/S1353802016300876.
- Carvalho CH, Kimmig H, Lopez WO, Lange M & Oeckler R. Hypertrophic Olivary Degeneration: A Neurosurgical Point of View. J Neurol Surg A Cent Eur Neurosurg. January, 2016; 77(1):59-62. https://www.ncbi.nlm.nih.gov/pubmed/26588253.