Rare Immunology News
Advertisement
Disease Profile
Congenital Zika syndrome
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
#N/A
Age of onset
#N/A
ICD-10
#N/A
Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
Zika syndrome
Categories
Viral infections
Summary
Symptoms
This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
Medical Terms | Other Names |
Learn More:
HPO ID
|
---|---|---|
80%-99% of people have these symptoms | ||
Maculopapular exanthema | 0040186 | |
30%-79% of people have these symptoms | ||
Abnormality of the cerebrospinal fluid | 0002921 | |
Arthralgia |
Joint pain
|
0002829 |
Joint inflammation
|
0001369 | |
Conjunctivitis |
Pink eye
|
0000509 |
Fever | 0001945 | |
Headache |
Headaches
|
0002315 |
Increased circulating IgM level | 0003496 | |
Myalgia |
Muscle ache
Muscle pain
[ more ] |
0003326 |
Pruritus |
Itching
Itchy skin
Skin itching
[ more ] |
0000989 |
5%-29% of people have these symptoms | ||
Ankle swelling | 0001785 | |
Edema |
Fluid retention
Water retention
[ more ] |
0000969 |
Transient hearing impairment | 0012779 | |
Vomiting |
Throwing up
|
0002013 |
Wrist swelling | 0001225 | |
1%-4% of people have these symptoms | ||
Abnormality of the optic disc | 0012795 | |
Absent foveal reflex | 0030825 | |
Acute demyelinating polyneuropathy | 0007131 | |
Chorioretinal atrophy | 0000533 | |
0006906 | ||
Encephalitis |
Brain inflammation
|
0002383 |
Intrauterine growth retardation |
Prenatal growth deficiency
Prenatal growth retardation
[ more ] |
0001511 |
Iris coloboma |
Cat eye
|
0000612 |
Lens subluxation |
Partially dislocated lens
|
0001132 |
Macular atrophy | 0007401 | |
0001287 | ||
Abnormally small skull
Decreased circumference of cranium
Decreased size of skull
Reduced head circumference
Small head circumference
[ more ] |
0000252 | |
Myelitis |
Inflammation of spinal cord
|
0012486 |
Optic disc hypoplasia | 0007766 | |
Retinal pigment epithelial mottling | 0007814 | |
Spontaneous abortion | 0005268 | |
Subcutaneous hemorrhage |
Bleeding below the skin
|
0001933 |
Low platelet count
|
0001873 |
Diagnosis
Making a diagnosis for a genetic or rare disease can often be challenging. Healthcare professionals typically look at a person’s medical history, symptoms, physical exam, and laboratory test results in order to make a diagnosis. The following resources provide information relating to diagnosis and testing for this condition. If you have questions about getting a diagnosis, you should contact a healthcare professional.
Testing Resources
- The Centers for Disease Control and Prevention has information on diagnostic testing for Zika
virus infection. - The Centers for Disease Control and Prevention has a feature which allows individuals to find their state health department.
Treatment
The resources below provide information about treatment options for this condition. If you have questions about which treatment is right for you, talk to your healthcare professional.
Management Guidelines
- The Centers for Disease Control and Prevention has posted Interim Guidelines for Health Care Professionals Caring for Pregnant Women and Women of Reproductive Age with Possible Zika
Virus Exposure.
Organizations
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Providing General Support
-
Centers for Disease Control and Prevention
1600 Clifton Road
Atlanta, GA 30329-4027
Toll-free: 800-CDC-INFO
TTY: 888-232-6348
Website: https://www.cdc.gov/
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- You can obtain general information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control measures to improve the health of the people of the United States. The CDC has updated information and videos on the Zika virus.
- March of Dimes has information on Congenital Zika syndrome.
In-Depth Information
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
References
- Congenital Zika Syndrome & Other Birth Defects. Centers for Disease Control and Prevention. Page last reviewed: November 27, 2017; https://www.cdc.gov/pregnancy/zika/testing-follow-up/zika-syndrome-birth-defects.html. Accessed 12/27/2017.
- Congenital Zika syndrome. March of Dimes. November 28, 2017; https://www.marchofdimes.org/complications/congenital-zika-syndrome.aspx. Accessed 12/27/2017.
- Areas with Zika. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention (CDC). February 9, 2016; https://www.cdc.gov/zika/geo/index.html.
- How to Protect Yourself. Centers for Disease Control and Prevention (CDC). March 18, 2016; https://www.cdc.gov/zika/pregnancy/protect-yourself.html.