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5 Facts you should know about
Scleroderma
1
Scleroderma is an autoimmune disorder that may involve changes in the skin, blood vessels, muscles, and internal organs
2
In addition to the skin, the most commonly affected organs are lungs and kidneys
3
It is characterized by increased synthesis of collagen (leading to sclerosis), damage to small blood vessels, activation of T lymphocytes, and production of altered connective tissue
4
Risk factors include family history, certain genetic factors, and exposure to silica
5
Women are more often affected than men – about 80% of cases
Rare Immunology News
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