5 Facts you should know about

CTLA4 deficiency

Most people with CTLA4 deficiency experience diarrhea or intestinal disease

Enlarged lymph nodes, liver, and spleen also are common, as are respiratory infections

People with CTLA4 deficiency often experience autoimmune problems that can affect various organs and tissues, including the blood, thyroid, skin, and joints

The disease also may slightly increase the risk of lymphoma

Current treatment for CTLA4 deficiency includes standard therapies for autoimmune problems and immunoglobulin deficiencies

Rare Immunology News