5 Facts you should know about

CARD9 deficiency

CARD9 deficiency is a genetic immune disorder characterized by susceptibility to fungal infections like candidiasis, which is caused by the yeast fungus Candida.

Many people with CARD9 deficiency develop systemic candidiasis that targets the central nervous system.

Age at onset is highly heterogeneous, ranging from childhood to adulthood for the same fungal disease.

CARD9 is expressed principally in myeloid cells.

CARD9 deficiency affects males and females in equal numbers and has been reported all over the world.

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